Research



Aim of the junior group SIAS is the establishment and apllication of new radiation sources on highly relevant issues in the field of structural infection biology. The obtained results are to be the key for struture-based drug design against selected infection diseases. The research of the group has three main focuses:

coherent imaging

Method Development

Development and adaption of coherent X-Ray imaging for biological molecules.
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coherent imaging

In Vivo Crystallization

Unreavaling the mechanisms of in vivo crystallization in Sf9 insect cells
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Prionfaltung

Prion Protein

Analysis of dynamic conformational changes of proteins involved in misfolding diseases.
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HCV

Viral Non-Structural Proteins

Structural-Functional analysis of viral non-structural proteins and their interactions with viral and host cell factors.
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